| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TNF receptor-associated factor 5 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRAF5 |
| Gene ID: |
7188 |
| Uniprot ID: |
TRAF5_HUMAN |
| Specificity: |
This antibody detects endogenous levels of TRAF5 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human TRAF5 |
| Post Translational Modifications | Ubiquitinated at Lys-318 by the SCF(FBXL2) complex, leading to its degradation by the proteasome. |
| Function | Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. |
| Protein Name | Tnf Receptor-Associated Factor 5Ring Finger Protein 84 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Tnf Receptor-Associated Factor 5 antibodyAnti-Ring Finger Protein 84 antibodyAnti-TRAF5 antibodyAnti-RNF84 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
