Host: |
Goat |
Applications: |
Pep-ELISA/WB/IHC |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-TRAF1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
IHC-2.5µg/mlELISA-antibody detection limit dilution 1:16000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
TRAF1 |
Gene ID: |
7185 |
Uniprot ID: |
TRAF1_HUMAN |
Immunogen Region: |
C-Term |
Accession Number: |
NP_005649.1 |
Immunogen Sequence: |
KLQSPKHAYVKDD |
Function | Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2. |
Protein Name | Tnf Receptor-Associated Factor 1Epstein-Barr Virus-Induced Protein 6 |
Database Links | Reactome: R-HSA-5357905Reactome: R-HSA-5357956 |
Alternative Antibody Names | Anti-Tnf Receptor-Associated Factor 1 antibodyAnti-Epstein-Barr Virus-Induced Protein 6 antibodyAnti-TRAF1 antibodyAnti-EBI6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance