Anti-TRAF1 antibody (191-240 aa) (STJ98606)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from TRAF1 at the amino acid range 191-240
General Information
| Short Description | Rabbit polyclonal anti-TNF receptor-associated factor 1 (191-240 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:10000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRAF1 |
| Gene ID | 7185 |
| Uniprot ID | TRAF1_HUMAN |
| Immunogen | Synthesized peptide derived from TRAF1 at the amino acid range 191-240 |
| Immunogen Region | 191-240 aa |
| Specificity | TRAF1 Polyclonal Antibody detects endogenous levels of TRAF1 |
Additional Info
| Function | Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2. |
| Protein Name | Tnf Receptor-Associated Factor 1Epstein-Barr Virus-Induced Protein 6 |
| Database Links | Reactome: R-HSA-5357905Reactome: R-HSA-5357956 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tnf Receptor-Associated Factor 1 antibodyAnti-Epstein-Barr Virus-Induced Protein 6 antibodyAnti-TRAF1 antibodyAnti-EBI6 antibody |
Information sourced from Uniprot.org