| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Thyroid peroxidase (651-700) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-p 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TPO |
| Gene ID: | 7173 |
| Uniprot ID: | PERT_HUMAN |
| Immunogen Region: | 651-700 |
| Specificity: | This antibody detects endogenous levels of Human Thyroperoxidase |
| Immunogen: | Synthesized peptide derived from human Thyroperoxidase AA range: 651-700 |
| Post Translational Modifications | Glycosylated. Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface. Cleaved in its N-terminal part. |
| Function | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). |
| Protein Name | Thyroid PeroxidaseTpo |
| Database Links | Reactome: R-HSA-209968 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell Surface |
| Alternative Antibody Names | Anti-Thyroid Peroxidase antibodyAnti-Tpo antibodyAnti-TPO antibody |
Information sourced from Uniprot.org