Anti-TPM4 antibody (127-177 aa) (STJ194771)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human TPM4 at the amino acid range 127-177
General Information
| Short Description | Rabbit polyclonal anti-Tropomyosin alpha-4 chain (127-177 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TPM4 |
| Gene ID | 7171 |
| Uniprot ID | TPM4_HUMAN |
| Immunogen | Synthesized peptide derived from the human TPM4 at the amino acid range 127-177 |
| Immunogen Region | 127-177 aa |
| Specificity | This antibody detects endogenous levels of TPM4 at Human/Mouse/Rat |
Additional Info
| Function | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium. Plays a role in platelet biogenesis. |
| Protein Name | Tropomyosin Alpha-4 ChainTm30p1Tropomyosin-4 |
| Database Links | Reactome: R-HSA-390522Reactome: R-HSA-445355Reactome: R-HSA-9013424Reactome: R-HSA-9725370 |
| Cellular Localisation | CytoplasmCytoskeletonAssociates With F-Actin Stress Fibers |
| Alternative Antibody Names | Anti-Tropomyosin Alpha-4 Chain antibodyAnti-Tm30p1 antibodyAnti-Tropomyosin-4 antibodyAnti-TPM4 antibody |
Information sourced from Uniprot.org