| Short Description : | Goat polyclonal antibody anti-TOX3 (N-Term) is suitable for use in ELISA research applications. |
| Applications: | Pep-ELISA |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Preliminary experiments gave an approx 100kDa band in HepG2 and U2OS cell lysates and in Human Cerebellum lysates after 0.2µg/ml antibody staining and was successfully blocked by incu |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TOX3 |
| Gene ID: | 27324 |
| Uniprot ID: | TOX3_HUMAN |
| Accession Number: | NP_001073899.2 |
| Immunogen Region: | N-Term |
| Immunogen Sequence: | AGDPASLDFAQC |
| Function | Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region. |
| Protein Name | Tox High Mobility Group Box Family Member 3Cag Trinucleotide Repeat-Containing Gene F9 ProteinTrinucleotide Repeat-Containing Gene 9 Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Tox High Mobility Group Box Family Member 3 antibodyAnti-Cag Trinucleotide Repeat-Containing Gene F9 Protein antibodyAnti-Trinucleotide Repeat-Containing Gene 9 Protein antibodyAnti-TOX3 antibodyAnti-CAGF9 antibodyAnti-TNRC9 antibody |
Information sourced from Uniprot.org
