Anti-TOR1AIP1 antibody (431-480 aa) (STJ93899)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TOR1AIP1 at the amino acid range 431-480
General Information
| Short Description | Rabbit polyclonal anti-Torsin-1A-interacting protein 1 (431-480 aa) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TOR1AIP1 |
| Gene ID | 26092 |
| Uniprot ID | TOIP1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TOR1AIP1 at the amino acid range 431-480 |
| Immunogen Region | 431-480 aa |
| Specificity | LAP1B Polyclonal Antibody detects endogenous levels of LAP1B protein. |
Additional Info
| Post Translational Modifications | Phosphorylated. Dephosphorylated at Ser-309 and Ser-315 by serine/threonine-protein phosphatase PP1. |
| Function | Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina. |
| Protein Name | Torsin-1a-Interacting Protein 1Lamin-Associated Protein 1bLap1b |
| Database Links | Reactome: R-HSA-9013405Reactome: R-HSA-9035034 |
| Cellular Localisation | Nucleus Inner MembraneSingle-Pass Membrane ProteinIsoform 4: Nucleus EnvelopeNucleusFound Mainly In The Nuclear Envelope And Also Inside The Nucleus |
| Alternative Antibody Names | Anti-Torsin-1a-Interacting Protein 1 antibodyAnti-Lamin-Associated Protein 1b antibodyAnti-Lap1b antibodyAnti-TOR1AIP1 antibodyAnti-LAP1 antibody |
Information sourced from Uniprot.org