Host: |
Rabbit |
Applications: |
WB/ELISA/IHC |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Torsin-1A-interacting protein 1 (431-480 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TOR1AIP1 |
Gene ID: |
26092 |
Uniprot ID: |
TOIP1_HUMAN |
Immunogen Region: |
431-480 aa |
Specificity: |
LAP1B Polyclonal Antibody detects endogenous levels of LAP1B protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human TOR1AIP1 at the amino acid range 431-480 |
Post Translational Modifications | Phosphorylated. Dephosphorylated at Ser-309 and Ser-315 by serine/threonine-protein phosphatase PP1. |
Function | Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina. |
Protein Name | Torsin-1a-Interacting Protein 1Lamin-Associated Protein 1bLap1b |
Database Links | Reactome: R-HSA-9013405Reactome: R-HSA-9035034 |
Cellular Localisation | Nucleus Inner MembraneSingle-Pass Membrane ProteinIsoform 4: Nucleus EnvelopeNucleusFound Mainly In The Nuclear Envelope And Also Inside The Nucleus |
Alternative Antibody Names | Anti-Torsin-1a-Interacting Protein 1 antibodyAnti-Lamin-Associated Protein 1b antibodyAnti-Lap1b antibodyAnti-TOR1AIP1 antibodyAnti-LAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance