| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TOMM7 |
| Gene ID: | 54543 |
| Uniprot ID: | TOM7_HUMAN |
| Immunogen Region: | 37-55 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-55 of human TOMM7 (NP_061932.1). |
| Immunogen Sequence: | MVKLSKEAKQRLQQLFKGSQ FAIRWGFIPLVIYLGFKRGA DPGMPEPTVLSLLWG |
| Function | Required for assembly and stability of the TOM complex. Positive regulator of PRKN translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria. |
| Protein Name | Mitochondrial Import Receptor Subunit Tom7 HomologTranslocase Of Outer Membrane 7 Kda Subunit Homolog |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-5205685 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Receptor Subunit Tom7 Homolog antibodyAnti-Translocase Of Outer Membrane 7 Kda Subunit Homolog antibodyAnti-TOMM7 antibodyAnti-TOM7 antibodyAnti-TOMM07 antibodyAnti-AD-014 antibody |
Information sourced from Uniprot.org