| Short Description : | Rabbit polyclonal TNXB (444-673) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNXB |
| Gene ID: | 7148 |
| Uniprot ID: | TENX_HUMAN |
| Immunogen Region: | 444-673 |
| Immunogen Sequence: | TSFTTGGLRIPFPRDCGEEM QNGAGASRTSTIFLNGNRER PLNVFCDMETDGGGWLVFQR RMDGQTDFWRDWEDYAHGFG NISGEFWLGNEALHSLTQAG DYSMRVDLRAGDEAVFAQYD SFHVDSAAEYYRLHLEGYHG TAGDSMSYHSGSVFSARDRD PNSLLISCAVSYRGAWWYRN CHYANLNGLYGSTVDHQGVS WYHWKGFEFSVPFTEMKLRP RNFRSPAGGG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 444-673 of human TNXB (NP_115859.2). |
| Tissue Specificity | Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB-short is only expressed in the adrenal gland. |
| Function | Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors. |
| Protein Name | Tenascin-XTn-XHexabrachion-Like Protein |
| Database Links | Reactome: R-HSA-3000178 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Tenascin-X antibodyAnti-Tn-X antibodyAnti-Hexabrachion-Like Protein antibodyAnti-TNXB antibodyAnti-HXBL antibodyAnti-TNX antibodyAnti-TNXB1 antibodyAnti-TNXB2 antibodyAnti-XB antibody |
Information sourced from Uniprot.org
