Anti-TNFSF13 antibody (105-247) (STJ25902)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TNFSF13 (105-247) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFSF13 |
| Gene ID | 8741 |
| Uniprot ID | TNF13_HUMAN |
| Immunogen Region | 105-247 |
| Immunogen Sequence | AVLTQKQKKQHSVLHLVPIN ATSKDDSDVTEVMWQPALRR GRGLQAQGYGVRIQDAGVYL LYSQVLFQDVTFTMGQVVSR EGQGRQETLFRCIRSMPSHP DRAYNSCYSAGVFHLHQGDI LSVIIPRARAKLNLSPHGTF LGL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 105-247 of human TNFSF13 (NP_742085.1). |
Additional Info
| Tissue Specificity | Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. |
| Post Translational Modifications | The precursor is cleaved by furin. |
| Function | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 13A Proliferation-Inducing LigandAprilTnf- And Apol-Related Leukocyte Expressed Ligand 2Tall-2Tnf-Related Death Ligand 1Trdl-1Cd Antigen Cd256 |
| Database Links | Reactome: R-HSA-450520Reactome: R-HSA-5669034 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 13 antibodyAnti-A Proliferation-Inducing Ligand antibodyAnti-April antibodyAnti-Tnf- And Apol-Related Leukocyte Expressed Ligand 2 antibodyAnti-Tall-2 antibodyAnti-Tnf-Related Death Ligand 1 antibodyAnti-Trdl-1 antibodyAnti-Cd Antigen Cd256 antibodyAnti-TNFSF13 antibodyAnti-APRIL antibodyAnti-TALL2 antibodyAnti-ZTNF2 antibodyAnti-UNQ383 antibodyAnti-PRO715 antibody |
Information sourced from Uniprot.org