• Immunofluorescence analysis of A549 cells, using CD253 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HUVEC cells and 293 cells, using CD253 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using TRAIL Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Anti-TNFSF10 antibody (31-80 aa) (STJ96086)

SKU:
STJ96086

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tumor necrosis factor ligand superfamily member 10 (31-80 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFSF10
Gene ID: 8743
Uniprot ID: TNF10_HUMAN
Immunogen Region: 31-80 aa
Specificity: TRAIL Polyclonal Antibody detects endogenous levels of TRAIL protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TNFSF10 at the amino acid range 31-80
Post Translational Modifications Tyrosine phosphorylated by PKDCC/VLK.
Function Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Protein Name Tumor Necrosis Factor Ligand Superfamily Member 10
Apo-2 Ligand
Apo-2l
Tnf-Related Apoptosis-Inducing Ligand
Protein Trail
Cd Antigen Cd253
Database Links Reactome: R-HSA-140534
Reactome: R-HSA-3371378
Reactome: R-HSA-5213460
Reactome: R-HSA-5218900
Reactome: R-HSA-69416
Reactome: R-HSA-75158
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Exists Both As Membrane-Bound And Soluble Form
Alternative Antibody Names Anti-Tumor Necrosis Factor Ligand Superfamily Member 10 antibody
Anti-Apo-2 Ligand antibody
Anti-Apo-2l antibody
Anti-Tnf-Related Apoptosis-Inducing Ligand antibody
Anti-Protein Trail antibody
Anti-Cd Antigen Cd253 antibody
Anti-TNFSF10 antibody
Anti-APO2L antibody
Anti-TRAIL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance