| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNFRSF6B |
| Gene ID: | 8771 |
| Uniprot ID: | TNF6B_HUMAN |
| Immunogen Region: | 200-300 |
| Immunogen Sequence: | PLSTRVPGAEECERAVIDFV AFQDISIKRLQRLLQALEAP EGWGPTPRAGRAALQLKLRR RLTELLGAQDGALLVRLLQA LRVARMPGLERSVRERFLPV H |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human TNFRSF6B (NP_003814.1). |
| Tissue Specificity | Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells. |
| Function | Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 6bDecoy Receptor 3Dcr3Decoy Receptor For Fas LigandM68 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 6b antibodyAnti-Decoy Receptor 3 antibodyAnti-Dcr3 antibodyAnti-Decoy Receptor For Fas Ligand antibodyAnti-M68 antibodyAnti-TNFRSF6B antibodyAnti-DCR3 antibodyAnti-TR6 antibodyAnti-UNQ186 antibodyAnti-PRO212 antibody |
Information sourced from Uniprot.org
