Name: Anti-TNFRSF1B antibody (376-425 aa) (STJ96053)
SKU: STJ96053
Availability: InStock

General Information
Product Properties
Target Information
Additional Info
Product Review

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Rabbit polyclonal antibody anti-Tumor necrosis factor receptor superfamily member 1B (376-425 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality :	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	TNFRSF1B
Gene ID:	7133
Uniprot ID:	TNR1B_HUMAN
Immunogen Region:	376-425 aa
Specificity:	TNF-R2 Polyclonal Antibody detects endogenous levels of TNF-R2 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human TNF Receptor II at the amino acid range 376-425

Function	Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 1b Tumor Necrosis Factor Receptor 2 Tnf-R2 Tumor Necrosis Factor Receptor Type Ii Tnf-Rii Tnfr-Ii P75 P80 Tnf-Alpha Receptor Cd Antigen Cd120b Etanercept Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1b - Membrane Form - Tumor Necrosis Factor-Binding Protein 2 Tbp-2 Tbpii
Database Links	Reactome: R-HSA-5668541 Reactome: R-HSA-5669034 Reactome: R-HSA-6783783 Reactome: R-HSA-6785807 Reactome: R-HSA-6798695
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 2: Secreted Tumor Necrosis Factor-Binding Protein 2: Secreted
Alternative Antibody Names	Anti-Tumor Necrosis Factor Receptor Superfamily Member 1b antibody Anti-Tumor Necrosis Factor Receptor 2 antibody Anti-Tnf-R2 antibody Anti-Tumor Necrosis Factor Receptor Type Ii antibody Anti-Tnf-Rii antibody Anti-Tnfr-Ii antibody Anti-P75 antibody Anti-P80 Tnf-Alpha Receptor antibody Anti-Cd Antigen Cd120b antibody Anti-Etanercept Cleaved Into - Tumor Necrosis Factor Receptor Superfamily Member 1b - Membrane Form - Tumor Necrosis Factor-Binding Protein 2 antibody Anti-Tbp-2 antibody Anti-Tbpii antibody Anti-TNFRSF1B antibody Anti-TNFBR antibody Anti-TNFR2 antibody

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJ94854	Anti-BCAR1 antibody (376-425 aa) (STJ94854)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC/IF/ELISA
STJ90765	Anti-Phospho-BCAR1-Tyr410 antibody (376-425 aa) (STJ90765)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC/IF/ELISA
STJ90745	Anti-Phospho-SMAD3-Ser425 antibody (376-425 aa) (STJ90745)	Rabbit	Polyclonal	Human/Mouse/Rat	IF/WB/IHC/ELISA
STJ90389	Anti-Phospho-PRKCZ-Thr410 antibody (376-425 aa) (STJ90389)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC/IF/ELISA
STJ94341	Anti-NACAD antibody (376-425) (STJ94341)	Rabbit	Polyclonal	Human/Rat/Mouse	WB/IHC

Anti-TNFRSF1B antibody (376-425 aa) (STJ96053)

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