Anti-TMPRSS11D antibody (STJ192136)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane protease serine 11D for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMPRSS11D |
| Gene ID | 9407 |
| Uniprot ID | TM11D_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | TM11D Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions.spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Preferentially cleaves the C-terminal side of arginine residues at the P1 position of certain peptides, cleaving Boc-Phe-Ser-Arg-4-methylcoumaryl-7-amide most efficiently and having an optimum pH of 8.6 with this substrate. |
| Protein Name | Transmembrane Protease Serine 11dAirway Trypsin-Like Protease Cleaved Into - Transmembrane Protease Serine 11d Non-Catalytic Chain - Transmembrane Protease Serine 11d Catalytic Chain |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinActivated By Cleavage And SecretedTransmembrane Protease Serine 11d Catalytic Chain: Secreted |
| Alternative Antibody Names | Anti-Transmembrane Protease Serine 11d antibodyAnti-Airway Trypsin-Like Protease Cleaved Into - Transmembrane Protease Serine 11d Non-Catalytic Chain - Transmembrane Protease Serine 11d Catalytic Chain antibodyAnti-TMPRSS11D antibodyAnti-HAT antibody |
Information sourced from Uniprot.org