Anti-TMOD4 antibody (1-345) (STJ28855)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TMOD4 (1-345) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMOD4 |
| Gene ID | 29765 |
| Uniprot ID | TMOD4_HUMAN |
| Immunogen Region | 1-345 |
| Immunogen Sequence | MSSYQKELEKYRDIDEDEIL RTLSPEELEQLDCELQEMDP ENMLLPAGLRQRDQTKKSPT GPLDREALLQYLEQQALEVK ERDDLVPFTGEKKGKPYIQP KREIPAEEQITLEPELEEAL AHATDAEMCDIAAILDMYTL MSNKQYYDALCSGEICNTEG ISSVVQPDKYKPVPDEPPNP TNIEEILKRVRSNDKELEEV NLNNIQDIPIPMLSELCEAM KANTYVRSFSLVATRSGDP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human TMOD4 (NP_037485.2). |
Additional Info
| Tissue Specificity | Highly expressed in skeletal muscle. |
| Function | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. |
| Protein Name | Tropomodulin-4Skeletal Muscle TropomodulinSk-Tmod |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | CytoplasmCytoskeletonIn Myofibrils With Sarcomeric StructureLocalizes To The Pointed End Of Actin Thin Filaments |
| Alternative Antibody Names | Anti-Tropomodulin-4 antibodyAnti-Skeletal Muscle Tropomodulin antibodyAnti-Sk-Tmod antibodyAnti-TMOD4 antibody |
Information sourced from Uniprot.org