Anti-TMOD1 antibody (STJA0007144)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TMOD1
General Information
| Short Description | Rabbit polyclonal anti-Tropomodulin-1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMOD1 |
| Gene ID | 7111 |
| Uniprot ID | TMOD1_HUMAN |
| Immunogen | Synthesized peptide derived from human TMOD1 |
| Specificity | This antibody detects endogenous levels of TMOD1 at Human, Mouse, Rat |
Additional Info
| Function | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. |
| Protein Name | Tropomodulin-1Erythrocyte TropomodulinE-Tmod |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | CytoplasmCytoskeletonIn Myofibrils With Sarcomeric StructureLocalizes To The Pointed End Of Actin Thin Filaments |
| Alternative Antibody Names | Anti-Tropomodulin-1 antibodyAnti-Erythrocyte Tropomodulin antibodyAnti-E-Tmod antibodyAnti-TMOD1 antibodyAnti-D9S57E antibodyAnti-TMOD antibody |
Information sourced from Uniprot.org