Western blot analysis of lysates from Mouse lung, using TMEM2 Rabbit polyclonal antibody (STJ11100393) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 3min.

Anti-TMEM2 antibody (1150-1250) (STJ11100393)

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STJ11100393
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CEMIP2
Gene ID: 23670
Uniprot ID: CEIP2_HUMAN
Immunogen Region: 1150-1250
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1150-1250 of human TMEM2 (NP_037522.1).
Immunogen Sequence: ERVKIQAATDSKDISNCMAK AYPQYYRKPSVVKRMPAMLT GLCQGCGTRQVVFTSDPHKS YLPVQFQSPDKAETQRGDPS VISVNGTDFTFRSAGVLLLV V
Tissue Specificity Widely expressed.
Function Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 10-5 kDa fragments. Very specific to hyaluronan.not able to cleave chondroitin sulfate or dermatan sulfate. Has an essential function in systemic hyaluronan catabolism and turnover and regulates cell adhesion and migration via hyaluronan degradation at focal adhesion sites. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling.
Protein Name Cell Surface Hyaluronidase Cemip2
Cell Migration-Inducing Hyaluronidase 2
Transmembrane Protein 2
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Cell Surface Hyaluronidase Cemip2 antibody
Anti-Cell Migration-Inducing Hyaluronidase 2 antibody
Anti-Transmembrane Protein 2 antibody
Anti-CEMIP2 antibody
Anti-KIAA1412 antibody
Anti-TMEM2 antibody

Information sourced from Uniprot.org

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