| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMEM132D |
| Gene ID: | 121256 |
| Uniprot ID: | T132D_HUMAN |
| Immunogen Region: | 730-915 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 730-915 of human TMEM132D (NP_597705.2). |
| Immunogen Sequence: | DFSLMATSLDEKVVSIHQDP KFKWPIIAAETEGQGTLVKV EMVISESCQKSKRKSVLAVG TANIKVKFGQNDANPNTSDS RHTGAGVHMENNVSDRRPKK PSQEWGSQEGQYYGSSSMGL MEGRGTTTDRSILQKKKGQE SLLDDNSHLQTIPSDLTSFP AQVDLPRSNGEMDGNDLMQA SKGLSD |
| Tissue Specificity | Expressed in mature oligodendrocytes. Detected in the brain, lung, pancreas and testis. Highly expressed in mature neurons of the adult nervous system. |
| Function | Regulate neuronals morphology via inhibition of the WAVE regulatory complex (WCR), a complex that controls F-actin cytoskeletal dynamics. |
| Protein Name | Transmembrane Protein 132dMature Oligodendrocytes Transmembrane ProteinMature Ol Transmembrane Protein |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Protein 132d antibodyAnti-Mature Oligodendrocytes Transmembrane Protein antibodyAnti-Mature Ol Transmembrane Protein antibodyAnti-TMEM132D antibodyAnti-HBE120 antibodyAnti-KIAA1944 antibodyAnti-MOLT antibody |
Information sourced from Uniprot.org