Anti-TMEM131L antibody (321-371 aa) (STJ195432)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human T131L at the amino acid range 321-371
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane protein 131-like (321-371 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMEM131L |
| Gene ID | 23240 |
| Uniprot ID | T131L_HUMAN |
| Immunogen | Synthesized peptide derived from the human T131L at the amino acid range 321-371 |
| Immunogen Region | 321-371 aa |
| Specificity | This antibody detects endogenous levels of T131L at Human/Mouse |
Additional Info
| Function | Isoform 1: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation. |
| Protein Name | Transmembrane Protein 131-Like |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmDuring Intrathymic DevelopmentResides In Punctate Cytoplasmic Structures In Dn1 And Dn2 CellsIn Dn3 CellsFound In Large Crescent-Shaped Membrane StructuresWhich Preferentially Localize In Cell-To-Cell Contact ZonesIsoform 1: Endoplasmic ReticulumTransmembrane Localization Is Essential For Wnt Signaling InhibitionIsoform 5: CytoplasmScattered Throughout The Cytoplasm In Small-Sized Punctate Structures |
| Alternative Antibody Names | Anti-Transmembrane Protein 131-Like antibodyAnti-TMEM131L antibodyAnti-KIAA0922 antibody |
Information sourced from Uniprot.org