Anti-TMEM119 antibody (STJA0006946)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TMEM119
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane protein 119 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMEM119 |
| Gene ID | 338773 |
| Uniprot ID | TM119_HUMAN |
| Immunogen | Synthesized peptide derived from human TMEM119 |
| Specificity | This antibody detects endogenous levels of TMEM119 at Human, Mouse |
Additional Info
| Function | Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation. |
| Protein Name | Transmembrane Protein 119Osteoblast Induction FactorObif |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmEndoplasmic Reticulum MembraneSecreted |
| Alternative Antibody Names | Anti-Transmembrane Protein 119 antibodyAnti-Osteoblast Induction Factor antibodyAnti-Obif antibodyAnti-TMEM119 antibodyAnti-PSEC0199 antibodyAnti-UNQ731 antibodyAnti-PRO1415 antibody |
Information sourced from Uniprot.org