| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-TMC7 (310-360 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Tmc7 |
| Gene ID: | 209760 |
| Uniprot ID: | TMC7_MOUSE |
| Immunogen Region: | 310-360 aa |
| Specificity: | Specific for TMC7. |
| Immunogen: | A synthetic peptide from aa region 310-360 of mouse TMC7 conjugated to blue carrier protein was used as the antigen. |
| Function | Acts as an inhibitory modulator of Piezo2 mechanosensitive channel in dorsal root ganglion (DRG) neurons through physical interactions or interference with the interaction between PIEZO2 and the cytoskeleton. |
| Protein Name | Transmembrane Channel-Like Protein 7 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Transmembrane Channel-Like Protein 7 antibodyAnti-Tmc7 antibody |
Information sourced from Uniprot.org