| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Transmembrane 4 L6 family member 19 (140-160 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA-Pep 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TM4SF19 |
| Gene ID: | 116211 |
| Uniprot ID: | T4S19_HUMAN |
| Immunogen Region: | 140-160 aa |
| Specificity: | This antibody detects endogenous levels of human TM4SF19 |
| Immunogen: | Synthesized peptide derived from the human TM4SF19 at the amino acid range 140-160 |
| Function | Negatively regulates vacuolar (H+)-ATPase (V-ATPase) activity by interacting with members of V-ATPase V0 complex and hence inhibiting V1-V0 complex assembly. Required for multinucleation during osteoclast differentiation. |
| Protein Name | Transmembrane 4 L6 Family Member 19Osteoclast Maturation-Associated Gene 4 ProteinTetraspan Membrane Protein Octm4 |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinCytoplasmCytoskeletonCell ProjectionFilopodiumIn OsteoclastsLocalizes Not Only To The Actin RingBut Also To The FilopodiaThe Stretched Structures For Searching Cells To FuseAnd The FusopodThe Cytoplasmic Bridge For Contacting Other Osteoclasts To Fuse |
| Alternative Antibody Names | Anti-Transmembrane 4 L6 Family Member 19 antibodyAnti-Osteoclast Maturation-Associated Gene 4 Protein antibodyAnti-Tetraspan Membrane Protein Octm4 antibodyAnti-TM4SF19 antibodyAnti-OCTM4 antibody |
Information sourced from Uniprot.org