| Short Description : | Rabbit polyclonal antibody anti-TLR13 (400-480) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications: | ELISA/IHC/IP/WB |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.68 µg/µl |
| Purification: | Affinity Purified |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:100 |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Tlr13 |
| Gene ID: | 279572 |
| Uniprot ID: | TLR13_MOUSE |
| Immunogen: | Synthetic peptide taken within amino acid region 400-480 of mouse TLR13 protein. |
| Immunogen Region: | 400-480 |
| Function | Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus.however, these data require additional evidences. |
| Protein Name | Toll-Like Receptor 13 |
| Cellular Localisation | Endosome MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Toll-Like Receptor 13 antibodyAnti-Tlr13 antibody |
Information sourced from Uniprot.org
