| Host: | Rabbit |
| Applications: | ELISA/WB |
| Reactivity: | Chimpanzee/Human/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-TLR12 (440-470) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | FITC |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.69 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:20, 000ELISA: 1:20, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Tlr12 |
| Gene ID: | 384059 |
| Uniprot ID: | TLR12_MOUSE |
| Immunogen Region: | 440-470 |
| Immunogen: | Synthetic peptide taken within amino acid region 440-470 from mouse TLR12 protein. |
| Tissue Specificity | Macrophages, liver, kidney and bladder epithelial cells. |
| Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system. |
| Protein Name | Toll-Like Receptor 12Toll-Like Receptor 11 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Toll-Like Receptor 12 antibodyAnti-Toll-Like Receptor 11 antibodyAnti-Tlr12 antibodyAnti-Gm1365 antibodyAnti-Tlr11 antibody |
Information sourced from Uniprot.org