| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Tight junction protein ZO-2 (1063-1112 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TJP2 |
| Gene ID: | 9414 |
| Uniprot ID: | ZO2_HUMAN |
| Immunogen Region: | 1063-1112 aa |
| Specificity: | ZO-2 Polyclonal Antibody detects endogenous levels of ZO-2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ZO-2 at the amino acid range 1063-1112 |
| Function | Plays a role in tight junctions and adherens junctions. Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity. |
| Protein Name | Tight Junction Protein 2Tight Junction Protein Zo-2Zona Occludens Protein 2Zonula Occludens Protein 2 |
| Database Links | Reactome: R-HSA-2028269Reactome: R-HSA-351906Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106 |
| Cellular Localisation | Cell JunctionAdherens JunctionCell MembranePeripheral Membrane ProteinCytoplasmic SideTight JunctionNucleusAlso Nuclear Under Environmental Stress Conditions And In Migratory Endothelial Cells And Subconfluent Epithelial Cell CulturesLocalizes To Tight Junctions During Initial Stages Of Their Formation |
| Alternative Antibody Names | Anti-Tight Junction Protein 2 antibodyAnti-Tight Junction Protein Zo-2 antibodyAnti-Zona Occludens Protein 2 antibodyAnti-Zonula Occludens Protein 2 antibodyAnti-TJP2 antibodyAnti-X104 antibodyAnti-ZO2 antibody |
Information sourced from Uniprot.org
