| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Tight junction protein ZO-2 (1063-1112 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TJP2 |
| Gene ID: | 9414 |
| Uniprot ID: | ZO2_HUMAN |
| Immunogen Region: | 1063-1112 aa |
| Specificity: | ZO-2 Polyclonal Antibody detects endogenous levels of ZO-2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ZO-2 at the amino acid range 1063-1112 |
| Function | Plays a role in tight junctions and adherens junctions. Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity. |
| Protein Name | Tight Junction Protein Zo-2Tight Junction Protein 2Zona Occludens Protein 2Zonula Occludens Protein 2 |
| Database Links | Reactome: R-HSA-2028269Reactome: R-HSA-351906Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106 |
| Cellular Localisation | Cell JunctionAdherens JunctionCell MembranePeripheral Membrane ProteinCytoplasmic SideTight JunctionNucleusAlso Nuclear Under Environmental Stress Conditions And In Migratory Endothelial Cells And Subconfluent Epithelial Cell Cultures |
| Alternative Antibody Names | Anti-Tight Junction Protein Zo-2 antibodyAnti-Tight Junction Protein 2 antibodyAnti-Zona Occludens Protein 2 antibodyAnti-Zonula Occludens Protein 2 antibodyAnti-TJP2 antibodyAnti-X104 antibodyAnti-ZO2 antibody |
Information sourced from Uniprot.org
