| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TIPARP |
| Gene ID: | 25976 |
| Uniprot ID: | PARPT_HUMAN |
| Immunogen Region: | 441-657 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 441-657 of human TIPARP (NP_056323.2). |
| Immunogen Sequence: | DGVTSANFYPETWVYMHPSQ DFIQVPVSAEDKSYRIIYNL FHKTVPEFKYRILQILRVQN QFLWEKYKRKKEYMNRKMFG RDRIINERHLFHGTSQDVVD GICKHNFDPRVCGKHATMFG QGSYFAKKASYSHNFSKKSS KGVHFMFLAKVLTGRYTMGS HGMRRPPPVNPGSVTSDLYD SCVDNFFEPQIFVIFNDDQS YPYFVIQYEEVSNTVSI |
| Post Translational Modifications | Auto-mono-ADP-ribosylated. |
| Function | ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins. Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR. |
| Protein Name | Protein Mono-Adp-Ribosyltransferase TiparpAdp-Ribosyltransferase Diphtheria Toxin-Like 14Artd14Poly Adp-Ribose Polymerase 7Parp-7Tcdd-Inducible Poly Adp-Ribose Polymerase |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Mono-Adp-Ribosyltransferase Tiparp antibodyAnti-Adp-Ribosyltransferase Diphtheria Toxin-Like 14 antibodyAnti-Artd14 antibodyAnti-Poly Adp-Ribose Polymerase 7 antibodyAnti-Parp-7 antibodyAnti-Tcdd-Inducible Poly Adp-Ribose Polymerase antibodyAnti-TIPARP antibodyAnti-PARP7 antibody |
Information sourced from Uniprot.org