Anti-TIP30/CC3 antibody (N-Term) (STJ70526)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-TIP30/CC3 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 28kDa band observed in lysates of cell line HeLa (calculated MW of 27.0kDa according to NP_006401.3). Recommended concentration: 0.3-1ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | HTATIP2 |
| Gene ID | 10553 |
| Uniprot ID | HTAI2_HUMAN |
| Accession Number | NP_001091990.1; NP_006401.3; NP_001091991.1; NP_001091992.1; NP_001091993.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | AETEALSKLREDFR |
| Specificity | This antibody is expected to recognise all three reported isoforms. Variants (NP_006401.3; NP_001091991.1; NP_001091992.1) encode the same isoform. |
Additional Info
| Function | Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. |
| Protein Name | Oxidoreductase Htatip230 Kda Hiv-1 Tat-Interacting ProteinHiv-1 Tat-Interactive Protein 2 |
| Cellular Localisation | CytoplasmNucleus Envelope |
| Alternative Antibody Names | Anti-Oxidoreductase Htatip2 antibodyAnti-30 Kda Hiv-1 Tat-Interacting Protein antibodyAnti-Hiv-1 Tat-Interactive Protein 2 antibodyAnti-HTATIP2 antibodyAnti-CC3 antibodyAnti-TIP30 antibody |
Information sourced from Uniprot.org