| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-TIP30/CC3 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 28kDa band observed in lysates of cell line HeLa (calculated MW of 27.0kDa according to NP_006401.3). Recommended concentration: 0.3-1µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HTATIP2 |
| Gene ID: | 10553 |
| Uniprot ID: | HTAI2_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_001091990.1; NP_006401.3; NP_001091991.1; NP_001091992.1; NP_001091993.1 |
| Specificity: | This antibody is expected to recognise all three reported isoforms. Variants (NP_006401.3; NP_001091991.1; NP_001091992.1) encode the same isoform. |
| Immunogen Sequence: | AETEALSKLREDFR |
| Function | Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. |
| Protein Name | Oxidoreductase Htatip230 Kda Hiv-1 Tat-Interacting ProteinHiv-1 Tat-Interactive Protein 2 |
| Cellular Localisation | CytoplasmNucleus Envelope |
| Alternative Antibody Names | Anti-Oxidoreductase Htatip2 antibodyAnti-30 Kda Hiv-1 Tat-Interacting Protein antibodyAnti-Hiv-1 Tat-Interactive Protein 2 antibodyAnti-HTATIP2 antibodyAnti-CC3 antibodyAnti-TIP30 antibody |
Information sourced from Uniprot.org
