Host: | Rabbit |
Applications: | IHC/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Mitochondrial import inner membrane translocase subunit Tim8 B (1-51 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IHC-P 1:50-200 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TIMM8B |
Gene ID: | 26521 |
Uniprot ID: | TIM8B_HUMAN |
Immunogen Region: | 1-51 aa |
Specificity: | This antibody detects endogenous levels of TIM8B at Human/Mouse/Rat |
Immunogen: | Synthesized peptide derived from the human TIM8B at the amino acid range 1-51 |
Function | Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. |
Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim8 B Ddp-Like Protein Deafness Dystonia Protein 2 |
Database Links | Reactome: R-HSA-1268020 |
Cellular Localisation | Mitochondrion Inner Membrane Peripheral Membrane Protein Intermembrane Side |
Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim8 B antibody Anti-Ddp-Like Protein antibody Anti-Deafness Dystonia Protein 2 antibody Anti-TIMM8B antibody Anti-DDP2 antibody Anti-DDPL antibody Anti-TIM8B antibody |
Information sourced from Uniprot.org