| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Mitochondrial import inner membrane translocase subunit Tim8 B (1-51 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TIMM8B |
| Gene ID: | 26521 |
| Uniprot ID: | TIM8B_HUMAN |
| Immunogen Region: | 1-51 aa |
| Specificity: | This antibody detects endogenous levels of TIM8B at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human TIM8B at the amino acid range 1-51 |
| Function | Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim8 BDdp-Like ProteinDeafness Dystonia Protein 2 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinIntermembrane Side |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim8 B antibodyAnti-Ddp-Like Protein antibodyAnti-Deafness Dystonia Protein 2 antibodyAnti-TIMM8B antibodyAnti-DDP2 antibodyAnti-DDPL antibodyAnti-TIM8B antibody |
Information sourced from Uniprot.org