Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: | TIMM21 |
Gene ID: | 29090 |
Uniprot ID: | TIM21_HUMAN |
Immunogen Region: | 1-248 aa |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-248 of human TIMM21 (NP_054896.2). |
Immunogen Sequence: | MICTFLRAVQYTEKLHRSSA KRLLLPYIVLNKACLKTEPS LRCGLQYQKKTLRPRCILGV TQKTIWTQGPSPRKAKEDGS KQVSVHRSQRGGTAVPTSQK VKEAGRDFTYLIVVLFGISI TGGLFYTIFKELFSSSSPSK IYGRALEKCRSHPEVIGVFG ESVKGYGEVTRRGRRQHVRF TEYVKDGLKHTCVKFYIEGS EPGKQGTVYAQVKENPGSGE YDFRYIFVEIESYPRRTII |
Function | Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes. |
Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim21Tim21-Like Protein - Mitochondrial |
Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9864848 |
Cellular Localisation | Mitochondrion MembraneSingle-Pass Membrane Protein |
Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim21 antibodyAnti-Tim21-Like Protein - Mitochondrial antibodyAnti-TIMM21 antibodyAnti-C18orf55 antibodyAnti-TIM21 antibodyAnti-HSPC154 antibody |
Information sourced from Uniprot.org