| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TIMM17A |
| Gene ID: | 10440 |
| Uniprot ID: | TI17A_HUMAN |
| Immunogen Region: | 72-171 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 72-171 of human TIMM17A (NP_006326.1). |
| Immunogen Sequence: | LFSMIDCSMVQVRGKEDPWN SITSGALTGAILAARNGPVA MVGSAAMGGILLALIEGAGI LLTRFASAQFPNGPQFAEDP SQLPSTQLPSSPFGDYRQYQ |
| Post Translational Modifications | Degraded by YMEL1 downstream of the integrated stress response (ISR). |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim17-AInner Membrane Preprotein Translocase Tim17a |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim17-A antibodyAnti-Inner Membrane Preprotein Translocase Tim17a antibodyAnti-TIMM17A antibodyAnti-MIMT17 antibodyAnti-TIM17 antibodyAnti-TIM17A antibodyAnti-TIMM17 antibody |
Information sourced from Uniprot.org