| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TIMM17A |
| Gene ID: |
10440 |
| Uniprot ID: |
TI17A_HUMAN |
| Immunogen Region: |
1-171 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-171 of human TIMM17A (NP_006326.1). |
| Immunogen Sequence: |
MEEYAREPCPWRIVDDCGGA FTMGTIGGGIFQAIKGFRNS PVGVNHRLRGSLTAIKTRAP QLGGSFAVWGGLFSMIDCSM VQVRGKEDPWNSITSGALTG AILAARNGPVAMVGSAAMGG ILLALIEGAGILLTRFASAQ FPNGPQFAEDPSQLPSTQLP SSPFGDYRQYQ |
| Post Translational Modifications | Degraded by YMEL1 downstream of the integrated stress response (ISR). |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim17-AInner Membrane Preprotein Translocase Tim17a |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim17-A antibodyAnti-Inner Membrane Preprotein Translocase Tim17a antibodyAnti-TIMM17A antibodyAnti-MIMT17 antibodyAnti-TIM17 antibodyAnti-TIM17A antibodyAnti-TIMM17 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and TIMM17A knockout (KO) 293T cells, using [KO Validated] TIMM17A Rabbit polyclonal antibody (STJ11100794) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89730/358208/STJ11100794_1__30814.1713122530.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TIMM17A knockout (KO) 293T cells, using [KO Validated] TIMM17A Rabbit polyclonal antibody (STJ11100794) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
