Anti-TIMM10B antibody (1-103) (STJ110786)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TIMM10B (1-103) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM10B |
| Gene ID | 26515 |
| Uniprot ID | T10B_HUMAN |
| Immunogen Region | 1-103 |
| Immunogen Sequence | MERQQQQQQQLRNLRDFLLV YNRMTELCFQRCVPSLHHRA LDAEEEACLHSCAGKLIHSN HRLMAAYVQLMPALVQRRIA DYEAASAVPGVAAEQPGVSP SGS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-103 of human TIMM10B (NP_036324.1). |
Additional Info
| Tissue Specificity | Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle. |
| Function | Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim10 BFracture Callus Protein 1Fxc1Mitochondrial Import Inner Membrane Translocase Subunit Tim9 BTimm10bTim10b |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim10 B antibodyAnti-Fracture Callus Protein 1 antibodyAnti-Fxc1 antibodyAnti-Mitochondrial Import Inner Membrane Translocase Subunit Tim9 B antibodyAnti-Timm10b antibodyAnti-Tim10b antibodyAnti-TIMM10B antibodyAnti-FXC1 antibodyAnti-TIM9B antibodyAnti-TIMM9B antibody |
Information sourced from Uniprot.org