| Tissue Specificity | Expressed by stimulated T-cells. Expressed during primary antigen stimulation. Expressed at higher levels on B rather than T-cells, both constitutively and after activation. |
| Function | Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation. May play a role in kidney injury and repair. |
| Protein Name | Hepatitis A Virus Cellular Receptor 1 HomologHavcr-1Kidney Injury Molecule 1Kim-1T Cell Immunoglobulin And Mucin Domain-Containing Protein 1Timd-1T Cell Membrane Protein 1T-Cell Immunoglobulin Mucin Receptor 1Tim-1Cd Antigen Cd365 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Hepatitis A Virus Cellular Receptor 1 Homolog antibodyAnti-Havcr-1 antibodyAnti-Kidney Injury Molecule 1 antibodyAnti-Kim-1 antibodyAnti-T Cell Immunoglobulin And Mucin Domain-Containing Protein 1 antibodyAnti-Timd-1 antibodyAnti-T Cell Membrane Protein 1 antibodyAnti-T-Cell Immunoglobulin Mucin Receptor 1 antibodyAnti-Tim-1 antibodyAnti-Cd Antigen Cd365 antibodyAnti-Havcr1 antibodyAnti-Kim1 antibodyAnti-Tim1 antibodyAnti-Timd1 antibody |
Information sourced from Uniprot.org
