Anti-Thrombopoietin/Tpo antibody (22-353 aa) [SRM] (STJ11107191)

SKU:
STJ11107191

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Monoclonal
Clone ID: SRM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: Thpo
Gene ID: 21832
Uniprot ID: TPO_MOUSE
Immunogen Region: 22-353 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 22-353 of mouse Thrombopoietin/Tpo (NP_033405.1).
Immunogen Sequence: SPVAPACDPRLLNKLLRDSH LLHSRLSQCPDVDPLSIPVL LPAVDFSLGEWKTQTEQSKA QDILGAVSLLLEGVMAARGQ LEPSCLSSLLGQLSGQVRLL LGALQGLLGTQLPLQGRTTA HKDPNALFLSLQQLLRGKVR FLLLVEGPTLCVRRTLPTTA VPSSTSQLLTLNKFPNRTSG LLETNFSVTARTAGPGLLSR LQGFRVKITPGQLNQTSRSP VQISGYLNRTHGPVNGTHG
Tissue Specificity Found mainly in the liver, kidney and skeletal muscle.
Function Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Protein Name Thrombopoietin
C-Mpl Ligand
Ml
Megakaryocyte Colony-Stimulating Factor
Megakaryocyte Growth And Development Factor
Mgdf
Myeloproliferative Leukemia Virus Oncogene Ligand
Cellular Localisation Secreted
Alternative Antibody Names Anti-Thrombopoietin antibody
Anti-C-Mpl Ligand antibody
Anti-Ml antibody
Anti-Megakaryocyte Colony-Stimulating Factor antibody
Anti-Megakaryocyte Growth And Development Factor antibody
Anti-Mgdf antibody
Anti-Myeloproliferative Leukemia Virus Oncogene Ligand antibody
Anti-Thpo antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance