| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | Thpo |
| Gene ID: | 21832 |
| Uniprot ID: | TPO_MOUSE |
| Immunogen Region: | 22-353 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-353 of mouse Thrombopoietin/Tpo (NP_033405.1). |
| Immunogen Sequence: | SPVAPACDPRLLNKLLRDSH LLHSRLSQCPDVDPLSIPVL LPAVDFSLGEWKTQTEQSKA QDILGAVSLLLEGVMAARGQ LEPSCLSSLLGQLSGQVRLL LGALQGLLGTQLPLQGRTTA HKDPNALFLSLQQLLRGKVR FLLLVEGPTLCVRRTLPTTA VPSSTSQLLTLNKFPNRTSG LLETNFSVTARTAGPGLLSR LQGFRVKITPGQLNQTSRSP VQISGYLNRTHGPVNGTHG |
| Tissue Specificity | Found mainly in the liver, kidney and skeletal muscle. |
| Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
| Protein Name | ThrombopoietinC-Mpl LigandMlMegakaryocyte Colony-Stimulating FactorMegakaryocyte Growth And Development FactorMgdfMyeloproliferative Leukemia Virus Oncogene Ligand |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Thrombopoietin antibodyAnti-C-Mpl Ligand antibodyAnti-Ml antibodyAnti-Megakaryocyte Colony-Stimulating Factor antibodyAnti-Megakaryocyte Growth And Development Factor antibodyAnti-Mgdf antibodyAnti-Myeloproliferative Leukemia Virus Oncogene Ligand antibodyAnti-Thpo antibody |
Information sourced from Uniprot.org