Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Monoclonal |
Clone ID: |
SRM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: |
Thpo |
Gene ID: |
21832 |
Uniprot ID: |
TPO_MOUSE |
Immunogen Region: |
22-353 aa |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-353 of mouse Thrombopoietin/Tpo (NP_033405.1). |
Immunogen Sequence: |
SPVAPACDPRLLNKLLRDSH LLHSRLSQCPDVDPLSIPVL LPAVDFSLGEWKTQTEQSKA QDILGAVSLLLEGVMAARGQ LEPSCLSSLLGQLSGQVRLL LGALQGLLGTQLPLQGRTTA HKDPNALFLSLQQLLRGKVR FLLLVEGPTLCVRRTLPTTA VPSSTSQLLTLNKFPNRTSG LLETNFSVTARTAGPGLLSR LQGFRVKITPGQLNQTSRSP VQISGYLNRTHGPVNGTHG |
Tissue Specificity | Found mainly in the liver, kidney and skeletal muscle. |
Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
Protein Name | ThrombopoietinC-Mpl LigandMlMegakaryocyte Colony-Stimulating FactorMegakaryocyte Growth And Development FactorMgdfMyeloproliferative Leukemia Virus Oncogene Ligand |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Thrombopoietin antibodyAnti-C-Mpl Ligand antibodyAnti-Ml antibodyAnti-Megakaryocyte Colony-Stimulating Factor antibodyAnti-Megakaryocyte Growth And Development Factor antibodyAnti-Mgdf antibodyAnti-Myeloproliferative Leukemia Virus Oncogene Ligand antibodyAnti-Thpo antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance