| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
SRM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
THRA |
| Gene ID: |
7067 |
| Uniprot ID: |
THA_HUMAN |
| Immunogen Region: |
119-199 aa |
| Specificity: |
Recombinant fusion protein containing a sequence within amino acids 119-199 of human THRA (NP_003241.2). |
| Immunogen Sequence: |
GMAMDLVLDDSKRVAKRKLI EQNRERRRKEEMIRSLQQRP EPTPEEWDLIHIATEAHRST NAQGSHWKQRRKFLPDDIGQ S |
| Function | Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. Isoform Alpha-2: Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action. |
| Protein Name | Thyroid Hormone Receptor AlphaNuclear Receptor Subfamily 1 Group A Member 1V-Erba-Related Protein 7Ear-7C-Erba-1C-Erba-Alpha |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-4090294 P10827-2 |
| Cellular Localisation | NucleusIsoform Alpha-2: CytoplasmWhen Overexpressed Found In The Cytoplasm Where It Colocalizes With Tacc1 |
| Alternative Antibody Names | Anti-Thyroid Hormone Receptor Alpha antibodyAnti-Nuclear Receptor Subfamily 1 Group A Member 1 antibodyAnti-V-Erba-Related Protein 7 antibodyAnti-Ear-7 antibodyAnti-C-Erba-1 antibodyAnti-C-Erba-Alpha antibodyAnti-THRA antibodyAnti-EAR7 antibodyAnti-ERBA1 antibodyAnti-NR1A1 antibodyAnti-THRA1 antibodyAnti-THRA2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
