| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-THPO (22-349) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
THPO |
| Gene ID: |
7066 |
| Uniprot ID: |
TPO_HUMAN |
| Immunogen Region: |
22-349 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 22-349 of human THPO (NP_001171068.1). |
| Immunogen Sequence: |
SPAPPACDLRVLSKLLRDSH VLHSRLSQCPEVHPLPTPVL LPAVDFSLGEWKTQMEETKA QDILGAVTLLLEGVMAARGQ LGPTCLSSLLGQLSGQVRLL LGALQSLLGTQGRTTAHKDP NAIFLSFQHLLRGKVRFLML VGGSTLCVRRAPPTTAVPSR TSLVLTLNELPNRTSGLLET NFTASARTTGSGLLKWQQGF RAKIPGLLNQTSRSLDQIPG YLNRIHELLNGTRGLFPGP |
| Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
| Protein Name | ThrombopoietinC-Mpl LigandMlMegakaryocyte Colony-Stimulating FactorMegakaryocyte Growth And Development FactorMgdfMyeloproliferative Leukemia Virus Oncogene Ligand |
| Database Links | Reactome: R-HSA-76009 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Thrombopoietin antibodyAnti-C-Mpl Ligand antibodyAnti-Ml antibodyAnti-Megakaryocyte Colony-Stimulating Factor antibodyAnti-Megakaryocyte Growth And Development Factor antibodyAnti-Mgdf antibodyAnti-Myeloproliferative Leukemia Virus Oncogene Ligand antibodyAnti-THPO antibodyAnti-MGDF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
