Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Protein THEMIS is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | THEMIS |
Gene ID: | 387357 |
Uniprot ID: | THMS1_HUMAN |
Specificity: | This antibody detects endogenous levels of TSEPA at Human, Mouse |
Immunogen: | Synthesized peptide derived from human TSEPA |
Function | Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. |
Protein Name | Protein ThemisThymocyte-Expressed Molecule Involved In Selection |
Cellular Localisation | CytoplasmNucleus |
Alternative Antibody Names | Anti-Protein Themis antibodyAnti-Thymocyte-Expressed Molecule Involved In Selection antibodyAnti-THEMIS antibodyAnti-C6orf190 antibodyAnti-C6orf207 antibody |
Information sourced from Uniprot.org