Anti-THEMIS antibody (1-50) {Biotin} (STJ503249)

Name: Anti-THEMIS antibody (1-50) {Biotin} (STJ503249)
SKU: STJ503249-100
Price: 497.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationBiotin

IsotypeIgG

ImmunogenSynthetic peptide taken within amino acid region 1-50 on Thymocyte-expressed molecule involved in selection protein.

STJ503249-100

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Short Description	Rabbit polyclonal antibody anti-THEMIS (1-50) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Applications	ELISA/IHC/IP/WB
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Biotin
Concentration	0.64-0.72 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	THEMIS
Gene ID	387357
Uniprot ID	THMS1_HUMAN
Immunogen	Synthetic peptide taken within amino acid region 1-50 on Thymocyte-expressed molecule involved in selection protein.
Immunogen Region	1-50

Post Translational Modifications	Phosphorylated on Tyr residues quickly after TCR stimulation.
Function	Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Protein Name	Protein Themis Thymocyte-Expressed Molecule Involved In Selection
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-Protein Themis antibody Anti-Thymocyte-Expressed Molecule Involved In Selection antibody Anti-THEMIS antibody Anti-C6orf190 antibody Anti-C6orf207 antibody

Information sourced from Uniprot.org