Anti-THEM4 antibody (STJA0009592)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CTMP
General Information
| Short Description | Rabbit polyclonal anti-Acyl-coenzyme A thioesterase THEM4 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | THEM4 |
| Gene ID | 117145 |
| Uniprot ID | THEM4_HUMAN |
| Immunogen | Synthesized peptide derived from human CTMP |
| Specificity | This antibody detects endogenous levels of CTMP at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. inhibits AKT1 phosphorylation and activity. enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane. |
| Protein Name | Acyl-Coenzyme A Thioesterase Them4Acyl-Coa Thioesterase Them4Carboxyl-Terminal Modulator ProteinThioesterase Superfamily Member 4 |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-165158Reactome: R-HSA-199418Reactome: R-HSA-389357Reactome: R-HSA-5218920Reactome: R-HSA-77289 |
| Cellular Localisation | Cell MembraneCell ProjectionRuffle MembraneCytoplasmMitochondrionMitochondrion Inner MembranePeripheral Membrane ProteinMitochondrion Intermembrane SpaceReleased From The Mitochondria Into The Cytosol In Response To Apoptotic Stimuli |
| Alternative Antibody Names | Anti-Acyl-Coenzyme A Thioesterase Them4 antibodyAnti-Acyl-Coa Thioesterase Them4 antibodyAnti-Carboxyl-Terminal Modulator Protein antibodyAnti-Thioesterase Superfamily Member 4 antibodyAnti-THEM4 antibodyAnti-CTMP antibody |
Information sourced from Uniprot.org