| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Acyl-coenzyme A thioesterase THEM4 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | THEM4 |
| Gene ID: | 117145 |
| Uniprot ID: | THEM4_HUMAN |
| Specificity: | This antibody detects endogenous levels of CTMP at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human CTMP |
| Post Translational Modifications | Phosphorylated. |
| Function | Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. inhibits AKT1 phosphorylation and activity. enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane. |
| Protein Name | Acyl-Coenzyme A Thioesterase Them4Acyl-Coa Thioesterase Them4Carboxyl-Terminal Modulator ProteinThioesterase Superfamily Member 4 |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-165158Reactome: R-HSA-199418Reactome: R-HSA-389357Reactome: R-HSA-5218920Reactome: R-HSA-77289 |
| Cellular Localisation | Cell MembraneCell ProjectionRuffle MembraneCytoplasmMitochondrionMitochondrion Inner MembranePeripheral Membrane ProteinMitochondrion Intermembrane SpaceReleased From The Mitochondria Into The Cytosol In Response To Apoptotic Stimuli |
| Alternative Antibody Names | Anti-Acyl-Coenzyme A Thioesterase Them4 antibodyAnti-Acyl-Coa Thioesterase Them4 antibodyAnti-Carboxyl-Terminal Modulator Protein antibodyAnti-Thioesterase Superfamily Member 4 antibodyAnti-THEM4 antibodyAnti-CTMP antibody |
Information sourced from Uniprot.org
