| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TGOLN2 |
| Gene ID: | 10618 |
| Uniprot ID: | TGON2_HUMAN |
| Immunogen Region: | 323-423 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 323-423 of human TGN46/TGN46/TGOLN2 (NP_006455.2). |
| Immunogen Sequence: | PKEAEDDDTGPEEGSPPKEE KEKMSGSASSENREGTLSDS TGSEKDDLYPNGSGNGSAES SHFFAYLVTAAILVAVLYIA HHNKRKIIAFVLEGKRSKVT R |
| Tissue Specificity | Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells. |
| Function | May be involved in regulating membrane traffic to and from trans-Golgi network. |
| Protein Name | Trans-Golgi Network Integral Membrane Protein 2Trans-Golgi Network Glycoprotein 46Tgn38 HomologHtgn46Trans-Golgi Network Glycoprotein 48Htgn48Trans-Golgi Network Glycoprotein 51Htgn51Trans-Golgi Network Protein 2 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-432722Reactome: R-HSA-6811440Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8957275 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinGolgi ApparatusTrans-Golgi Network MembranePrimarily In Trans-Golgi NetworkCycles Between The Trans-Golgi Network And The Cell Surface Returning Via Endosomes |
| Alternative Antibody Names | Anti-Trans-Golgi Network Integral Membrane Protein 2 antibodyAnti-Trans-Golgi Network Glycoprotein 46 antibodyAnti-Tgn38 Homolog antibodyAnti-Htgn46 antibodyAnti-Trans-Golgi Network Glycoprotein 48 antibodyAnti-Htgn48 antibodyAnti-Trans-Golgi Network Glycoprotein 51 antibodyAnti-Htgn51 antibodyAnti-Trans-Golgi Network Protein 2 antibodyAnti-TGOLN2 antibodyAnti-TGN46 antibodyAnti-TGN51 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and ERCC1 knockout (KO) HeLa cells, using [KO Validated] ERCC1 Rabbit polyclonal antibody (STJ11100039) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89111/357565/STJ11100039_1__56308.1713121691.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ERCC1 knockout (KO) HeLa cells, using [KO Validated] ERCC1 Rabbit polyclonal antibody (STJ11100039) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.")
