Host: | Rabbit |
Applications: | CM/ELISA/ICC/IHC/IF/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-TGM1 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunohistochemistry, Immunofluorescence and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
Purification: | Affinity Purified |
Concentration: | 0.61-0.65 µg/µl |
Dilution Range: | WB: 1:450DB: 1:30, 000ELISA: 1:30, 000IHC: 1:250ICC: 1:250IF: 1:250CFM: 1:250 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | F13a1 |
Gene ID: | 74145 |
Uniprot ID: | F13A_MOUSE |
Immunogen: | Synthetic peptide corresponding to unique amino acid sequence on Coagulation factor XIIIA chain precursor |
Post Translational Modifications | The activation peptide is released by thrombin. |
Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
Protein Name | Coagulation Factor Xiii A ChainCoagulation Factor XiiiaProtein-Glutamine Gamma-Glutamyltransferase A ChainTransglutaminase A Chain |
Database Links | Reactome: R-MMU-114608Reactome: -MMU-140875 |
Cellular Localisation | CytoplasmSecretedSecreted Into The Blood PlasmaCytoplasmic In Most TissuesBut Also Secreted In The Blood Plasma |
Alternative Antibody Names | Anti-Coagulation Factor Xiii A Chain antibodyAnti-Coagulation Factor Xiiia antibodyAnti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibodyAnti-Transglutaminase A Chain antibodyAnti-F13a1 antibodyAnti-F13a antibody |
Information sourced from Uniprot.org