![Anti-TGF-alpha antibody [1E8-G6] (STJ16101006)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149722/302463/STJ16101006_1__16844.1646940648.jpg?c=1 "Anti-TGF-alpha antibody [1E8-G6] (STJ16101006)")
![Anti-TGF-alpha antibody [1E8-G6] (STJ16101006)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149722/302463/STJ16101006_1__16844.1646940648.jpg?c=1 "Anti-TGF-alpha antibody [1E8-G6] (STJ16101006)")
Anti-TGF-alpha antibody [1E8-G6] (STJ16101006)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgMk
ImmunogenA BALB/c mouse was immunized with synthetic TGF-alpha 34-43 decapeptide linked carrier. Fusion partner: Sp2/0-Ag14.
General Information
| Short Description | Mouse monoclonal anti-TGF-alpha for use in ELISA, FC, WB and IHC in Human, Rabbit and Zebrafish samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC/WB/IHC |
| Host | Mouse |
| Reactivity | Human/Rabbit/Zebrafish |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1E8-G6 |
| Isotype | IgMk |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | ELISA (solid phase: not known; tracer: 0.001-100 ยตg/ml for 30 min at RT). Flow cytometry (0, 5-1, 0 Mu g/million cells in 0, 1ml). Immunoblotting (1-2 Mu g/ml). Immunohistology (1-2 ยตg/ml for 30 min at RT; staining of formalin-fixed tissues requires |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8ยฐC upon receipt. |
Target Information
| Gene Symbol | TGFA |
| Gene ID | 7039 |
| Uniprot ID | TGFA_HUMAN |
| Immunogen | A BALB/c mouse was immunized with synthetic TGF-alpha 34-43 decapeptide linked carrier. Fusion partner: Sp2/0-Ag14. |
Additional Info
| Tissue Specificity | Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines. |
| Function | TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. |
| Protein Name | Protransforming Growth Factor Alpha Cleaved Into - Transforming Growth Factor AlphaTgf-AlphaEgf-Like TgfEtgfTgf Type 1 |
| Database Links | Reactome: R-HSA-1257604Reactome: R-HSA-177929Reactome: R-HSA-179812Reactome: R-HSA-180292Reactome: R-HSA-180336Reactome: R-HSA-182971Reactome: R-HSA-204005Reactome: R-HSA-212718Reactome: R-HSA-2219530Reactome: R-HSA-5638303Reactome: R-HSA-5673001Reactome: R-HSA-5694530Reactome: R-HSA-6811558Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8866910Reactome: R-HSA-9009391Reactome: R-HSA-9018519Reactome: R-HSA-9634638 |
| Cellular Localisation | Transforming Growth Factor Alpha: SecretedExtracellular SpaceProtransforming Growth Factor Alpha: Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Protransforming Growth Factor Alpha Cleaved Into - Transforming Growth Factor Alpha antibodyAnti-Tgf-Alpha antibodyAnti-Egf-Like Tgf antibodyAnti-Etgf antibodyAnti-Tgf Type 1 antibodyAnti-TGFA antibody |
Information sourced from Uniprot.org