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Polyclonal Antibodies
Anti-TFDP1 antibody (361-410 aa) (STJ95976)

Western blot analysis of lysates from HeLa cells, using DP-1 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of HeLa cells, using DP-1 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using DP-1 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of various cells using TFDP1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-TFDP1 antibody (361-410 aa) (STJ95976)

SKU:

STJ95976

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Transcription factor Dp-1 (361-410 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	TFDP1
Gene ID:	7027
Uniprot ID:	TFDP1_HUMAN
Immunogen Region:	361-410 aa
Specificity:	TFDP1 Polyclonal Antibody detects endogenous levels of TFDP1 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human DP-1 at the amino acid range 361-410

Post Translational Modifications	Phosphorylation by E2F1-bound cyclin A-CDK2, in the S phase, inhibits E2F-mediated DNA binding and transactivation. Ubiquitinated by the BCR(KBTBD5) complex, leading to its subsequent degradation.
Function	Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTCCGCGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters.
Protein Name	Transcription Factor Dp-1 Drtf1-Polypeptide 1 Drtf1 E2f Dimerization Partner 1
Database Links	Reactome: R-HSA-111448 Reactome: R-HSA-113501 Reactome: R-HSA-1362277 Reactome: R-HSA-1362300 Reactome: R-HSA-139915 Reactome: R-HSA-1538133 Reactome: R-HSA-1912408 Reactome: R-HSA-2173796 Reactome: R-HSA-2559580 Reactome: R-HSA-2559585 Reactome: R-HSA-6804114 Reactome: R-HSA-69202 Reactome: R-HSA-69205 Reactome: R-HSA-69231 Reactome: R-HSA-69656 Reactome: R-HSA-8953750 Reactome: R-HSA-9616222 Reactome: R-HSA-9661069
Cellular Localisation	Nucleus Cytoplasm Shuttles Between The Cytoplasm And Nucleus And Translocates Into The Nuclear Compartment Upon Heterodimerization With E2f1
Alternative Antibody Names	Anti-Transcription Factor Dp-1 antibody Anti-Drtf1-Polypeptide 1 antibody Anti-Drtf1 antibody Anti-E2f Dimerization Partner 1 antibody Anti-TFDP1 antibody Anti-DP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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