| Host: | Goat |
| Applications: | Pep-ELISA/WB/IF/FC |
| Reactivity: | Human/Mouse/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-TFAP2D (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx. 48kDa band observed in nuclear lysates of cell line NIH3T3 and approx. 50kDa in Human Ovary lysates, and in preliminary testing of Human Placenta lysate (calculated MW of 49.5k |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TFAP2D |
| Gene ID: | 83741 |
| Uniprot ID: | AP2D_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_758438.2 |
| Immunogen Sequence: | HHQSFHYEFQHSHP |
| Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. |
| Protein Name | Transcription Factor Ap-2-DeltaAp2-DeltaActivating Enhancer-Binding Protein 2-DeltaTranscription Factor Ap-2-Beta-Like 1 |
| Database Links | Reactome: R-HSA-8866904Reactome: R-HSA-8866907 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Ap-2-Delta antibodyAnti-Ap2-Delta antibodyAnti-Activating Enhancer-Binding Protein 2-Delta antibodyAnti-Transcription Factor Ap-2-Beta-Like 1 antibodyAnti-TFAP2D antibodyAnti-TFAP2BL1 antibody |
Information sourced from Uniprot.org