• Western blot analysis of various lysates using TFAP2C Rabbit polyclonal antibody (STJ110050) at 1:1000 dilution. Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/ proteins: 25 Mu g per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection:ECL Basic Kit. Exposuretime: 60s.

Anti-TFAP2C antibody (350-450) (STJ110050)

SKU:
STJ110050

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TFAP2C (350-450) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TFAP2C
Gene ID: 7022
Uniprot ID: AP2C_HUMAN
Immunogen Region: 350-450
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TFAP2C (NP_003213.1).
Immunogen Sequence: NMLLAAQQLCKEFTELLSQD RTPHGTSRLAPVLETNIQNC LSHFSLITHGFGSQAICAAV SALQNYIKEALIVIDKSYMN PGDQSPADSNKTLEKMEKHR K
Post Translational Modifications Sumoylated on Lys-10.which inhibits transcriptional activity.
Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Protein Name Transcription Factor Ap-2 Gamma
Ap2-Gamma
Activating Enhancer-Binding Protein 2 Gamma
Transcription Factor Erf-1
Database Links Reactome: R-HSA-3232118
Reactome: R-HSA-8866904
Reactome: R-HSA-8866906
Reactome: R-HSA-8866907
Reactome: R-HSA-8866910
Reactome: R-HSA-8866911
Reactome: R-HSA-9827857
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor Ap-2 Gamma antibody
Anti-Ap2-Gamma antibody
Anti-Activating Enhancer-Binding Protein 2 Gamma antibody
Anti-Transcription Factor Erf-1 antibody
Anti-TFAP2C antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance