Anti-TENM3 antibody (STJA0004848)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human TENM3
General Information
| Short Description | Rabbit polyclonal antibody anti-Teneurin-3 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IHC 1:100-1:300 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TENM3 |
| Gene ID | 55714 |
| Uniprot ID | TEN3_HUMAN |
| Immunogen | Synthetic peptide of human TENM3 |
Additional Info
| Tissue Specificity | Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nucleus, followed by thalamus and subthalamic nucleus. |
| Function | Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion. Required for proper dendrite morphogenesis and axon targeting in the vertebrate visual system, thereby playing a key role in the development of the visual pathway. Regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May also be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes. |
| Protein Name | Teneurin-3Ten-3Protein Odd Oz/Ten-M Homolog 3Tenascin-M3Ten-M3Teneurin Transmembrane Protein 3 |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinCell ProjectionAxon |
| Alternative Antibody Names | Anti-Teneurin-3 antibodyAnti-Ten-3 antibodyAnti-Protein Odd Oz/Ten-M Homolog 3 antibodyAnti-Tenascin-M3 antibodyAnti-Ten-M3 antibodyAnti-Teneurin Transmembrane Protein 3 antibodyAnti-TENM3 antibodyAnti-KIAA1455 antibodyAnti-ODZ3 antibodyAnti-TNM3 antibody |
Information sourced from Uniprot.org